Head & Neck SACT regimens:

Whilst every effort is made to ensure the accuracy of the information in a given regimen it cannot be guaranteed that the regimen is fully up to date, because of the dynamic nature of cancer treatment. Check the regimen details for the specific indication the regimen may be used / funded in. See our disclaimer.

Paclitaxel may be administered via a DEHP free line instead of the polyethylene lined giving set specified in the regimens.

Squamous with radiotherapy

• Carboplatin with concurrent RT
• Cetuximab with concurrent RT
• Cisplatin (40) with concurrent RT
• Cisplatin (100) with concurrent RT
• Pembrolizumab with concurrent RT (neoadjuvant then adjuvant)
• Pembrolizumab Cisplatin (40) with concurrent RT (neoadjuvant then adjuvant)
• Pembrolizumab Cisplatin (100) with concurrent RT (neoadjuvant then adjuvant)

Squamous neoadjuvant

• Carboplatin Fluorouracil
• Cisplatin Fluorouracil (CF100)

Squamous metastatic

• Carboplatin Fluorouracil
• Cisplatin Docetaxel Fluorouracil
• Cisplatin Fluorouracil (CF80)
• Docetaxel
• Methotrexate weekly
• Nivolumab
• Paclitaxel weekly
• Pembrolizumab

Oral cavity advanced

• • Carboplatin Fluorouracil
  • Cetuximab Cisplatin Fluorouracil
  • Cetuximab maintenance
  • Cisplatin Docetaxel Fluorouracil

Nasopharynx

• Gemcitabine Cisplatin

Cisplatin hydration

• Cisplatin hydration

SACT regimens written by S Coutts

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